Recent Research Trends against Skin Carcinoma - An Overview
- Authors: Varshney K.1, Mazumder R.2, Rani A.3, Mishra R.4, Khurana N.5
-
Affiliations:
- , Noida Institute of Engineering and Technology (Pharmacy Institute)
- Pharmacy Institute, Noida Institute of Engineering and Technology
- Pharmacy Institute, Noida Institute of Engineering and Technology (Pharmacy Institute)
- Department of Biotechnology, Noida Institute of Engineering and Technology
- School of Pharmaceutical Sciences, Lovely Professional University
- Issue: Vol 30, No 34 (2024)
- Pages: 2685-2700
- Section: Immunology, Inflammation & Allergy
- URL: https://vestnikugrasu.org/1381-6128/article/view/645939
- DOI: https://doi.org/10.2174/0113816128307653240710044902
- ID: 645939
Cite item
Full Text
Abstract
Skin cancer is a prevalent and sometimes lethal cancer that affects a wide range of people. UV radiation exposure is the main cause of skin cancer. Immunosuppression, environmental factors, and genetic predisposition are other contributing variables. Fair-skinned people and those with a history of sunburns or severe sun exposure are more likely to experience this condition. Melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC) are the three main forms. Melanoma poses a bigger hazard because of its tendency for metastasis, while SCC and BCC have limited metastatic potential. Genetic mutations and changes to signalling pathways such as p53 and MAPK are involved in pathogenesis. Early diagnosis is essential, and molecular testing, biopsy, dermoscopy, and visual inspection can all help. In addition to natural medicines like curcumin and green tea polyphenols, treatment options include immunotherapy, targeted therapy, radiation, surgery, and chemotherapy. Reducing the incidence of skin cancer requires preventive actions, including sun protection and early detection programs. An overview of skin cancers, including their forms, pathophysiology, diagnosis, and treatment, highlighting herbal therapy, is given in this review.
About the authors
Kamya Varshney
, Noida Institute of Engineering and Technology (Pharmacy Institute)
Email: info@benthamscience.net
Rupa Mazumder
Pharmacy Institute, Noida Institute of Engineering and Technology
Author for correspondence.
Email: info@benthamscience.net
Anjna Rani
Pharmacy Institute, Noida Institute of Engineering and Technology (Pharmacy Institute)
Email: info@benthamscience.net
Rashmi Mishra
Department of Biotechnology, Noida Institute of Engineering and Technology
Email: info@benthamscience.net
Navneet Khurana
School of Pharmaceutical Sciences, Lovely Professional University
Email: info@benthamscience.net
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