Advancing Novel Strategies against Post-surgical Tendon Adhesion Bands, Exploring New Frontiers
- Autores: Alaei M.1, Abdulhasan D.1, Barjasteh A.2, Al-Asady A.3, Latifi H.2, Vahedi E.4, Avan A.5, Khazaei M.5, Ryzhikov M.6, Hassanian S.1
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Afiliações:
- Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences
- Faculty of Medicine, Mashhad University of Medical Sciences
- Department of Medical Sciences, Faculty of Nursing, Warith Al-Anbiyaa University
- Orthopedic Research Center, Shahid Kamyab Hospital, Mashhad University of Medical Sciences
- Metabolic Syndrome Research Center, Mashhad University of Medical Sciences
- School of Medicine, Saint Louis University
- Edição: Volume 30, Nº 21 (2024)
- Páginas: 1650-1658
- Seção: Immunology, Inflammation & Allergy
- URL: https://vestnikugrasu.org/1381-6128/article/view/645789
- DOI: https://doi.org/10.2174/0113816128299091240423121840
- ID: 645789
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Texto integral
Resumo
Current interest in adhesion formation stems from its global impact on the function and quality of life, spanning a spectrum of subtle impairments to significant disabilities, based on the affected area and the extent of adhesion. Yet therapeutic agents are restricted to prophylactic anti-inflammatories, revision surgeries, and biological and physical techniques, none of which grant a decent outcome. Recent advancements in tissue- engineered biomaterials, drug delivery systems, and fabricating technologies such as nanoparticles, hydrogels, and weaving or braiding demonstrate potential for improved outcomes. However, none of the mentioned methods have reliable outcomes, thus this study aims to elucidate the mechanisms involved in the pathophysiology of tendon adhesion and post-surgical adhesion band formation (PSAB), with a closer look at inflammatory pathways stimulating the process. This article consolidates information on diverse therapeutic and prophylactic methods and cutting-edge technologies, aiming to provide a comprehensive update on this topic, and providing researchers an avenue for new and innovative ideas for further investigations.
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Sobre autores
Maryam Alaei
Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences
Email: info@benthamscience.net
Doaa Abdulhasan
Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences
Email: info@benthamscience.net
Amirhossein Barjasteh
Faculty of Medicine, Mashhad University of Medical Sciences
Email: info@benthamscience.net
Abdulridha Al-Asady
Department of Medical Sciences, Faculty of Nursing, Warith Al-Anbiyaa University
Email: info@benthamscience.net
Hanieh Latifi
Faculty of Medicine, Mashhad University of Medical Sciences
Email: info@benthamscience.net
Ehsan Vahedi
Orthopedic Research Center, Shahid Kamyab Hospital, Mashhad University of Medical Sciences
Email: info@benthamscience.net
Amir Avan
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences
Email: info@benthamscience.net
Majid Khazaei
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences
Email: info@benthamscience.net
Mikhail Ryzhikov
School of Medicine, Saint Louis University
Email: info@benthamscience.net
Seyed Hassanian
Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences
Autor responsável pela correspondência
Email: info@benthamscience.net
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