Reactions of 5(4Н)-oxazolones involving organosilone reagents

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Abstract

The review summarizes, systematizes and analyzes published literature data concerning the reactions of saturated and unsaturated 5(4H)-oxazolones with various organosilicon reagents. Examples of the preparation of heterocyclic compounds, 4,4-disubstituted 5(4H)-oxazolones, α,α-disubstituted α-amino acids and their esters using these reactions are considered. For some processes, transformation mechanisms are given. Examples of the synthesis of biologically active and natural compounds based on reactions involving 5(4H)-oxazolones and organosilicon reagents are presented.

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About the authors

V. O. Topuzyan

Institute of Fine Organic Chemistry of the Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia

Author for correspondence.
Email: vtop@web.am
ORCID iD: 0000-0002-1721-1993
Armenia, Yerevan, ave. Azatutyan, 26

A. A. Hovannesyan

Institute of Fine Organic Chemistry of the Scientific and Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia

Email: vtop@web.am
ORCID iD: 0000-0003-0879-6800
Armenia, Yerevan, ave. Azatutyan, 26

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