One-Time Definition of Biologically Active Components of Rhodiola rosea in Extracts of Plant Sources by HILIC-MS/MS Method

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Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

A simple, rapid and highly sensitive method for the simultaneous determination of the main components of Rhodiola rosea (rosin, salidroside, rosarin, and rosavin) in a wide range of concentrations by hydrophilic chromatography-tandem mass spectrometry has been developed. The conditions for extraction (type and composition of extractant, extraction time) of the main components from Rhodiola rosea root samples, chromatographic separation and detection of these compounds were selected, and the metrological characteristics of the proposed approach were evaluated. The detection limits were 250, 2.4, 2.3, and 5.4 ng/mL, and the linear ranges of detectable concentrations are 1–100, 0.01–10, 0.01–10, and 0.01–100 µg/mL for rosin, salidroside, rosarin, and rosavin, respectively. The developed approach is tested in the analysis of real samples of pharmaceuticals and plant raw materials.

Авторлар туралы

S. Nuikin

Lomonosov Moscow State University

Email: yury_tim@mail.ru

chemistry department

Ресей, Moscow

Yu. Timchenko

Lomonosov Moscow State University

Хат алмасуға жауапты Автор.
Email: yury_tim@mail.ru

chemistry department

Ресей, Moscow

I. Rodin

Lomonosov Moscow State University

Email: yury_tim@mail.ru

chemistry department

Ресей, Moscow

Әдебиет тізімі

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